EZGel: A Regenerative Injectable Made From Your Own Blood
- SEAPORT MEDSPA
- Dec 30, 2025
- 3 min read

EZGel is a regenerative injectable created entirely from your own blood and designed to improve skin quality while also providing soft, natural volume support. It sits within a category of treatments that focus on working with your body’s biology—supporting collagen, skin strength, and tissue integrity—rather than relying solely on synthetic materials.
Many patients are drawn to EZGel because it uses only what your body already produces, offering a natural approach with the added benefit of gentle structural support.
What Is EZGel?
EZGel is an advanced form of platelet-rich fibrin (PRF). It’s created by drawing a small amount of your blood and processing it to concentrate platelets, fibrin, and growth factors, your body naturally uses to repair tissue and stimulate collagen production.
What makes EZGel unique is an additional controlled heating and cooling process that transforms PRF into a smooth, injectable gel. This gel consistency allows EZGel to provide more structure and volume support than traditional PRF, while still remaining completely natural.
EZGel is:
Made entirely from your own blood
Free of synthetic fillers, additives, or preservatives
Regenerative and biologic
Capable of providing subtle volume support in addition to improving skin quality
How EZGel Works
EZGel supports the skin in two important ways:
Regenerative Support: The growth factors within EZGel stimulate collagen and elastin production, helping to improve skin thickness, texture, and overall quality over time.
Structural Support: Because EZGel has a gel-like consistency, it also provides soft immediate volume. This helps support delicate areas while the regenerative process takes place.
This dual action is what distinguishes EZGel from traditional PRF injections and makes it a unique option for patients who want more support than PRF alone, but a different feel and behavior than dermal filler.
How the EZGel Treatment Is Performed
Blood Draw: A small blood sample is taken, similar to routine lab work.
Processing: The blood is spun and refined to isolate platelet-rich fibrin.
EZGel Formation: The PRF is gently transformed into a smooth gel consistency.
Injection: EZGel is injected into targeted areas using precise, anatomy-based technique.
Appointments typically take about 45–60 minutes from start to finish.
Common Areas Treated with EZGel
EZGel is versatile and can be used in multiple areas of the face where improving skin quality and providing gentle support is the goal.
Under-Eyes: EZGel is commonly used under the eyes to improve crepey texture, fine lines, and skin quality while also providing soft volume support. This can help improve hollowing without creating a firm or overfilled appearance.
Lips: In the lips, EZGel enhances hydration, softness, and overall lip quality. It also offers subtle volume support, making it ideal for patients who want natural-looking enhancement rather than dramatic size or shape change.
Cheeks: EZGel can be used in the cheeks to support tissue structure and improve skin resilience. The gel provides gentle volume and scaffolding while collagen production improves over time.
Smile Lines (Nasolabial Folds): When placed in the smile line area, EZGel helps support the tissue and soften creasing by combining subtle volume support with collagen stimulation.
Single Area vs. Multiple Areas in One Treatment
EZGel treatments are customized based on your goals and anatomy.
A single area (such as under-eyes alone) can be treated effectively.
Multiple areas—for example under-eyes, cheeks, and smile lines—can be treated in the same session.
Your provider will help determine the most appropriate treatment plan based on your skin quality, facial structure, and desired outcome.
Treatment Schedule & Maintenance
For optimal results, EZGel is typically performed as a short series:
Initial Series: Two treatments spaced 6–8 weeks apart
Maintenance: One treatment approximately every 12 months
This schedule allows both the regenerative benefits and volume support to build gradually and remain consistent over time.
EZGel, PRF, and Dermal Fillers: How They Differ
These treatments serve different—but complementary—roles:
PRF Injections: Focus primarily on collagen stimulation and skin quality, with minimal volume support.
PRF EZGel: Improves skin quality and provides soft, natural volume support using your own biologic material.
Dermal Fillers: Provide more defined structure, contour, and longer-lasting volume.
Many patients benefit from one treatment alone or a combination approach, depending on anatomy, goals, and timeline.
Why Patients Choose EZGel
Patients often choose EZGel because:
It uses only their own blood
No synthetic products are injected
It offers both regenerative benefits and subtle volume support
Results develop naturally and gradually
It supports long-term skin quality and tissue health
EZGel is especially appealing for patients who value a natural approach and want balanced, understated improvement.
Is EZGel Right for You?
EZGel is well suited for patients looking to:
Improve skin quality and texture
Address early volume changes naturally
Enhance delicate areas with soft support
Take a regenerative, long-term approach to facial aging
